Cape compound used by the pharmaceutical factory in Foshan in Guangdong and the United States MSD company's compound enalapril tablets for the treatment of hypertension effects, the results of both domestic and imported medicines in the medication dose, taking methods, medication Courses are the same circumstances, there are one hundred percent efficiency, adverse reaction rates have not significantly different.
Isosorbide dinitrate respectively, will be the first biochemical Shanghai Pharmaceutical Company and the German pharmaceutical production Watts-isosorbide dinitrate injection 20 mg 5% glucose injection 500 ml, to patients with angina pectoris intravenous drip Note a day, medication for 14 days. After the results of the use of Chinese medicine in patients with clinical symptoms and ECG to improve the overall efficiency were 94.1% and 48.0%, 96.0% for imports of drugs and 52.0 percent, showed that the two drugs similar to the effect, there is no significant difference.
Verapamil with domestic and imported verapamil sustained-release in the treatment of mild to moderate hypertension, results in the efficiency of China-made drugs for 50 percent of the total effective relief for 90 percent, and import the drugs significantly efficiency of 50 percent, down Pressure total efficiency of 80 per cent, two of the side effects of similar drugs.
5 - single-isosorbide dinitrate with Shandong Lunan pharmaceutical laboratories and production of 5 - isosorbide labor in the treatment of angina, the total efficiency were 98%, 80% and 100 %, 85%, between the two drugs There was no significant difference, there is no significant difference in adverse reactions.
Digoxin to the pharmaceutical factory in Hangzhou people's livelihood and the British Wellcome production of digoxin films bioavailability tests, the results of the two drugs pharmacokinetic parameters of the difference was not significant that the two are entirely equivalent.
Terazosin second pharmaceutical plant in Beijing and the U.S. company Abbott production of terazosin hydrochloride tablets were human pharmacokinetics and bioavailability of comparison, the results of the products relative to imports of bioavailability was 104.49 %, Other pharmacokinetic parameters were not significantly different, indicating that two formulations are bioequivalent.
Nimodipine by Shandong Xinhua Pharmaceutical Factory and the Bayer company of Germany nimodipine injection stability, the stability that the two products in general, the difference was not significant.
Ticlopidine to Beijing Haier-Pharmaceutical Co., Ltd. and France's Sanofi company ticlopidine hydrochloride, a human pharmacokinetics and bioavailability of comparative studies, the results of two agents there was no significant difference between that Two formulations are bioequivalent. In addition, the Shanghai Pharmaceutical Co., Ltd. Xudong Haipu products with the French company Sanofi products hemorheology evaluation, no difference in the two results, show that domestic and imported ticlopidine also has better anti-platelet aggregation.
Clarithromycin patients with respiratory tract infections will be divided into two groups, the treatment group oral clarithromycin domestic, import control group of oral clarithromycin, the results of the two groups of cure rates were 77.3% and 72.7%. The two groups have a mild case of nausea and adverse reaction rates of 4.5 percent.
Cefoperazone of Taiyuan pharmaceutical factory production cefoperazone with the United States Pfizer Limited production of a drug cefoperazone dynamics comparison. The results of the two products in each time blood concentration data is very close to that in the two Pharmacokinetics basically the same process.
Levofloxacin group of new pharmaceutical factory in Zhejiang Beijing Stethoscope products for 109 cases, the control group used Japan's imports of 70 cases, according to each 200 mg, twice daily administration, for 5 to 7 days. Results efficient 87.2 percent, 86.9 percent clearance rate of bacteria, the adverse reaction rate of 13.6 percent in the control group of the three indicators were 85.7%, 88.4% and 12.9%. That domestic and imported levofloxacin oral treatment of acute bacterial infections equally safe and effective.
Azithromycin In order to compare domestic and imported azithromycin for the treatment of non-gonococcal urethritis effect, and Beijing Ocean medicine and Croatia's Pliva Pharmaceuticals products were treating 23 and 21 patients, both single oral dose 1 g treatment. The results showed that the two groups cure rates were 82.6% and 85.7%, respectively, the efficiency of 95.2% and 91.3%. This shows that domestic and imported azithromycin Stethoscope in the treatment of Feilin urethritis similar effect, there was no significant difference.
Haishu Bi (Shupu D) the use of the waterfront Pharmaceutical Co., Ltd. of Shenzhen will Haishu (including cefoperazone and sulbactam the 0.5 grams) and Dalian Pfizer pharmaceutical companies (and the National Product in the same) Shupu Deep, randomized controlled treatment of 128 cases of lower respiratory tract and urinary tract infection patients, two groups of the same dose, 2 grams each, dissolved in 10 percent of intravenous glucose injection, twice daily, 7 to 14 days of treatment. Haishu there must be a result of the efficiency of 89.06 percent, bacterial clearance rate for 86.89 percent, adverse reaction rates to 7.81 percent, Shupu depth of the three indicators were 89.06%, 85.0% and 7.81%, there was no significant difference.
Roxithromycin caused by the roxithromycin Mingan Jun 90 cases of patients with acute infection, controlled trial, two of the 45 cases, respectively, oral domestic and imported roxithromycin, dosage are 150 mg, twice daily, Treatment for seven to 14 days. The results of the domestic roxithromycin efficiency was 91.9%, bacterial clearance rate was 90.3 percent, adverse reaction rates to 2.22 percent, and imports from the above three roxithromycin index was 93.3%, 94.6% and 4.44%, there was no Significant difference.
Ofloxacin ear drops by 120 cases of acute otitis media-blind patients were randomly divided into two groups, the treatment group of 80 cases, 40 cases of control. Henan Medical University laboratories were used in the production of ofloxacin ear drops by 0.3 percent and Japan's Pharmaceutical Co.,Stethoscope Ltd. 0.3% levofloxacin in the treatment of ear drops, are used every four to six drops per day 3 , And seven days of treatment methods. The result is the total efficiency of the treatment group was 96%, 98% for the control group, two groups of similar effect.